Accuracy of Neutrophil-to-Lymphocyte Ratio in Predicting the Severity of Acute Appendicitis: A Single-Center Retrospective Study

Objective: Investigate the potential use of the neutrophil-to-lymphocyte ratio (NLR) in the identification and differentiation of acute appendicitis patients, specifically between simple and complicated presentations.Methods: An observational retrospective cohort study was conducted in Aseer Central...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-09, Vol.15 (9), p.e45923-e45923
Main Authors: Al Amri, Fahad S, Fihrah, Raneem S, Al Jabbar, Imtinan, Alqahtani, Rawan, Alnujaymi, Bayan, Alshehri, Renad M, Asiri, Sarah S
Format: Article
Language:English
Subjects:
Age groups
Appendicitis
Blood
General Surgery
Hematology
Lymphocytes
Neutrophils
Standard deviation
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Summary:Objective: Investigate the potential use of the neutrophil-to-lymphocyte ratio (NLR) in the identification and differentiation of acute appendicitis patients, specifically between simple and complicated presentations.Methods: An observational retrospective cohort study was conducted in Aseer Central Hospital, Saudi Arabia.Results: In total, 103 patients were included in this study, in which males (50.5%) were more common than females (49.5%), and the most common age group was found to be 36-45 years (56.3%), followed by 18-25 years (23.3%). All patients (100%) had a diagnosis of acute appendicitis. The means of neutrophils, lymphocytes, and NLR were found to be 68.970%, 22.067%, and 5.020, respectively. The majority (69%) had non-complicated appendicitis, while (31%) had complications. A significant association was seen between NLR and the occurrence of complications (p-value = 0.00001).Conclusion: This study can comprehensively support the evidence presented in the literature review. The use of the NLR demonstrates a notable level of accuracy in diagnosing acute appendicitis and differentiating between complex and uncomplicated cases.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.45923