Mood, Behavioral Impairment, and Sleep Breathing Disorders in Obstructive Sleep Apnea Syndrome Patients Treated with Maxillomandibular Advancement: Reflection on a Case Series and Review of Literature

The correlation between depressive and cognitive symptoms and OSAS (obstructive sleep apnea syndrome) is between 5 and 63%. We reported the case of two patients with severe OSAS and its associated depressive symptoms that were intolerant to continuous positive airway pressure (C-PAP) and underwent m...

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Bibliographic Details
Published in:Journal of personalized medicine 2023-09, Vol.13 (10), p.1425
Main Authors: Stilo, Giovanna, Lo Faro, Carmelo, Pollicina, Isabella, Falcone, Loredana, Campagna, Paola, Felis, Silvia, Crimi, Salvatore, La Mantia, Ignazio, Leonardi, Rosalia, Bianchi, Alberto
Format: Article
Language:English
Subjects:
Anxiety
Apnea
Cardiac arrhythmia
Cardiovascular disease
Care and treatment
Cognitive ability
Continuous positive airway pressure
Emotional disorders
Executive function
Hypertension
Hypoxia
Mechanical ventilation
Memory
Mental depression
Mood disorders
Patients
Precision medicine
Quality of life
Questionnaires
Sleep and wakefulness
Sleep apnea
Sleep apnea syndromes
Sleep disorders
Surgery
Surveys
Type 2 diabetes
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Summary:The correlation between depressive and cognitive symptoms and OSAS (obstructive sleep apnea syndrome) is between 5 and 63%. We reported the case of two patients with severe OSAS and its associated depressive symptoms that were intolerant to continuous positive airway pressure (C-PAP) and underwent maxillomandibular advancement (MMA) surgery. The severity of cognitive and depressive symptoms was assessed using validated questionnaires (Beck Depression Inventory, Beck Anxiety Inventory, Epworth Sleepiness Scale, and quality of life), medical observation, and patient-reported symptoms. We performed pre- and post-treatment polysomnography. Six months after treatment, the value of the apnea–hypopnea index (AHI) had returned to the normal range and, together with it, the depressive component was considerably reduced and the patients’ overall quality of life (BDI, BAI, ESS, and qol) improved. Conclusion: We described significant improvement in all the analyzed parameters, such as physical and mental functioning, and depression and anxiety rates.
ISSN:2075-4426
2075-4426
DOI:10.3390/jpm13101425