366 Effects of Acidosis Bout Events on Animal Growth and Development, and the Effectiveness of Liver Abscess-Controlling Antibiotic on Diminishing Its Incidence

• Published in: Journal of animal science 2023-11, Vol.101 (Supplement_3), p.296-297
• Main Authors: Batista, Luiz Fernando Dias, Rivera, Madeline E, Tedeschi, Luis O
• Format: Article
• Language: English
• Subjects: Abscesses; Acidosis; Animal growth; Animals; Beef; Beef cattle; Binary data; Cattle; Correlation; Dairy cattle; Data analysis; Diet; Dry matter; Effectiveness; Feed conversion; Feedlots; Feeds; Fermentation; Liver; Mathematical models; Metabolic disorders; Organic acids; pH effects; Rumen; Statistical analysis; Statistical models; Virginiamycin
• ISSN: 0021-8812; 1525-3163
• DOI: 10.1093/jas/skad281.353

Abstract Ruminal acidosis is a common metabolic disorder that affects feedlot and dairy cattle and occurs when the supply of organic acids from fermentation exceeds its absorption, accumulating acid content in the rumen. Virginiamycin (VM) has inhibitory effects on primary liver abscess-causing bacteria. In feedlot animals, dietary VM has been shown to reduce rumen acidosis and improve feed conversion actively. This study evaluated ruminal pH over 150 days on feed (DOF) of growing and finishing beef cattle and investigated the relationships between ruminal pH and growth and development outcomes and the effectiveness of the continuous or intermittent provision of VM in 120 Angus-crossbred steers. Steers received VM (240 mg/d) as follows: no VM (T000); VM in the last 50 d (T001); VM for the last 100 d (T011); VM in the first 50 d (T100); VM in the first 100 d (T110); and VM for 150 d (T111). Animals were fed a grower-type diet (metabolizable energy [ME]: 2.45 Mcal/kg; crude protein [CP]: 12.2 % dry matter basis [DM]) for 50 d before the adaptation of a finisher-type diet (ME: 2.60 Mcal/kg; CP: 10.6% DM) over a 17-d period. The finisher-type diet was fed for the remaining 84 days. On d -1 and d 82 each animal received an indwelling pH bolus to record ruminal pH at 10-min intervals. Acidosis bout event was categorized as if the pH stayed below 5.6 for 3 hours. Data were analyzed using a random coefficient statistical model, binary data was analyzed using the logit link function and correlations were analyzed using PROC CORR in SAS (Table 1). Duration under pH 5.8 and 5.6 tended to have a negative correlation with gain to feed (G/F; P ≤ 0.080), and % of the time that pH remained below 5.6 when under 5.8 was negatively correlated with G/F (P = 0.007) and tended to have a negative correlation with average daily gain (ADG; P = 0.081). Similarly, acidosis bouts event and duration of bout event (DURB) tended (P ≤ 0.074) to have a negative correlation with G/F, while ADG was negatively correlated (P = 0.035). The number of acidosis bout events and probability of acidosis bout events to occur increase linearly (R2 = 0.89, P < 0.001, and R2 = 0.77; P < 0.001, respectively) as DOF progressed. The probability of an acidosis bout event decreased by 46% for the T111 treatment compared with T000 (35.43% vs. 18.82%; P = 0.049). Acidosis bout event seems to affect the growth and development of beef steers negatively, and it appears to be more critical as DOF progress. Adminis