Morphea Involving the Lips and Gingiva: A Rare Case Report

Morphea is a subtype of scleroderma that does not involve Raynaud's phenomenon or internal organ involvement. It is a connective tissue disease that features the excessive deposition of collagen in the dermis and subcutaneous tissue, leading to a thickening of the dermis and subcutaneous tissue...

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Published in:Curēus (Palo Alto, CA) CA), 2023-12, Vol.15 (12), p.e51202
Main Authors: Albagieh, Hamad, Alshagroud, Rana S, Aladnan, Abdullah M, Aldosari, Bader, Alburaykan, Yara B, Almashham, Lama Y, Alqasem, Afyaa A, Alyahya, Areen A, Aboheimed, Nada I
Format: Article
Language:English
Subjects:
Blood vessels
Case reports
Connective tissue
Dentistry
Oral hygiene
Oral Medicine
Pathology
Scleroderma
Skin diseases
Steroids
Teeth
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Summary:Morphea is a subtype of scleroderma that does not involve Raynaud's phenomenon or internal organ involvement. It is a connective tissue disease that features the excessive deposition of collagen in the dermis and subcutaneous tissue, leading to a thickening of the dermis and subcutaneous tissue, eventually forming a scar-like lesion. We represent a 19-year-old male Saudi patient displaying a white patch on the marginal gingiva of tooth #21 and multiple yellowish papules on the outer surface of the lip. Both teeth #21 and #22 have experienced recession and bone loss. The patient's clinical history and histopathology revealed characteristic features of localized scleroderma. A treatment was proposed involving immunosuppressants, methotrexate, and pimecrolimus cream along with topical corticosteroids and excimer laser therapy (308 nm). The patient followed the treatment plan for a full month and the white patch quickly improved for the patient. Afterward, the patient has been taking only methotrexate with a significant but gradual improvement. In this paper, we discuss the differential diagnosis to be considered and present an unusual occurrence of localized scleroderma in the oral cavity.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.51202