Predictors of Cognitive Decline in 85-Year-Old Patients Without Cognitive Impairment at Baseline: 2-Year Follow-Up of the Octabaix Study

Background/Rationale: To determine how many 85-year-old community-dwelling patients with good cognitive performance at baseline maintain this level at 2-year follow-up. Methods: We realized a longitudinal community-based study including 169 inhabitants. Patients who maintained scores >23 on the S...

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Bibliographic Details
Published in:American journal of Alzheimer's disease and other dementias 2013-03, Vol.28 (2), p.147-153
Main Authors: Formiga, Francesc, Ferrer, Assumpta, Chivite, David, Alburquerque, Jesus, Olmedo, Claudia, Mora, Jose Maria, Labori, María, Pujol, Ramón
Format: Article
Language:English
Subjects:
Aged, 80 and over
Aging - physiology
Aging - psychology
Cognition - physiology
Cognition Disorders - diagnosis
Cohort Studies
Current Topic in Management
Disease Progression
Female
Follow-Up Studies
Geriatric Assessment
Humans
Logistic Models
Male
Mental Status Schedule
Prospective Studies
Risk Factors
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Summary:Background/Rationale: To determine how many 85-year-old community-dwelling patients with good cognitive performance at baseline maintain this level at 2-year follow-up. Methods: We realized a longitudinal community-based study including 169 inhabitants. Patients who maintained scores >23 on the Spanish version of the Mini-Mental State Examination (MEC) were compared with the rest. Results: A total of 144 individuals (85.2%) were found maintaining a MEC score >23. Under the combined criteria 110 (65%) presented no new cognitive decline. Multiple logistic regression analysis showed that maintaining a MEC score >23 was significantly associated with having a higher MEC score at baseline (P < .001, odds ratio 1.280, 95% confidence interval 1.104-1.484). Conclusion: Most oldest-old patients with good cognitive function at baseline maintain this level at 2-year follow-up.
ISSN:1533-3175
1938-2731
DOI:10.1177/1533317512475021