Uterine smooth muscle tumors of uncertain malignant potential (STUMP): A case report

• Published in: International journal of surgery case reports 2024-05, Vol.118, p.109607, Article 109607
• Main Authors: El Hassouni, Fatima, Tligui, Samia, Lakhdissi, Asmaa, Rouas, Lamiaa, El Youssfi, Mounia
• Format: Article
• Language: English
• Subjects: Atypical leiomyoma; Case Report; Leiomyosarcoma; STUMP; Uterine smooth muscle tumor of uncertain malignant potential
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2024.109607

Uterine smooth muscle tumors of uncertain malignant potential (STUMP) are extremely rare, defined as a uterine smooth muscle tumors that cannot be diagnosed as benign or malignant and does not satisfy all the criteria for leiomyosarcoma or leiomyoma. A 48-year-old woman who presented with a history of heavy menstrual bleeding and pelvic pain. Physical examination revealed an enlarged uterus. Ultrasonography showed lobular and enlarged uterus containing multiples leiomyomas. A subtotal hysterectomy was performed. A Pathological analysis revealed a uterine mass diagnosed as a smooth muscle tumor of uncertain malignant. Uterine STUMPs are rare and are commonly diagnosed by histopathological evaluation following myomectomy or hysterectomy. The most common clinical manifestations of uterine STUMP are the same as leiomyomas. Prognosis for the patient is unclear and there is a risk of recurrence with the tumors. However, considering their potential risk of recurrence and metastasis, it is advisable to maintain six-monthly controls for 5 years and then annual controls for 5 years more. Due to the rarity of uterine STUMP, there are no specific guidelines for their treatment and control. The scientific literature needs to be constantly updated in order to identify masses suspected of malignancy before surgery and improve patient management and follow-up. •Uterine smooth muscle of uncertain malignant potential (STUMP) are extremely rare•Uterine STUMPs are commonly diagnosed by histopatholological evaluation following myomectomy or hysterectomy.•Total hysterectomy is an optimal treatment for stumps among women without a desire of fertility to prevent recurrences.•All uterine STUMP cases should be the object of a multidisciplinary approach