Sensing of Quercetin With Cobalt-Doped Manganese Nanosystems by Electrochemical Method

• Published in: Curēus (Palo Alto, CA) CA), 2024-03, Vol.16 (3), p.e56665-e56665
• Main Authors: Thalir, Sree, Celshia Susai, Sherin, Selvamani, Muthamizh, Suresh, Vasugi, Sethuraman, Sathya, Ramalingam, Karthikeyan
• Format: Article
• Language: English
• Subjects: Biosensors; Chemical reactions; Cobalt; Dentistry; Electrodes; Healthcare Technology; Medical Physics; Morphology; Scanning electron microscopy; Sensors; Spectrum analysis; Voltammetry
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.56665

The pressing need for precise, quick, and affordable detection of diverse biomolecules has led to notable developments in the realm of biosensors. Quercetin, a biomolecule rich in flavonoids predominantly found in our diet, is sensed by the electrochemical method. The electrochemical properties show remarkable improvement when Mn O (MO) is doped with cobalt (Co).  Aim: This study aimed to investigate the biomolecule sensing of quercetin using Co-doped MO by electrochemical method.  Materials and methods: Co-doped MO nanospheres were prepared by hydrothermal method. The crystal structure of the synthesized material was evaluated by using X-ray diffraction analysis. The sample morphology was assessed by using field emission scanning electron microscopy (FE-SEM) techniques. The cyclic voltammetry technique was used for the detection of quercetin biomolecules.  Results: The synthesized Co-doped MO appeared to be spherical in morphology in FE-SEM. Energy-dispersive X-ray spectroscopy showed the only presence of Co, Mn, and O, which confirmed the purity of the sample. The modified electrode sensed the biomolecule with a higher current of 7.35 µA than the bare glassy carbon electrode of 6.1 µA. The Co-doped MO exhibited enhanced conductivity, reactivity, and electrochemical performance. This tailored approach will help in the optimization of material properties toward specific biomolecule sensing applications.