Unveiling rarity: Myoepithelioma in the minor salivary gland of buccal mucosa - A case report

• Published in: International journal of surgery case reports 2024-07, Vol.120, p.109849, Article 109849
• Main Authors: Sakhariya, Samkit V., Chincholkar, Anuja, Waknis, Pushkar P., Tidke, Sanika, Setiya, Sneha
• Format: Article
• Language: English
• Subjects: Buccal fat pad; Case Report; Immunohistochemistry; Minor salivary gland; Myoepithelioma
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2024.109849

Tumours of salivary glands are rare and have various histo-pathological subtypes. Myoepitheliomas were first classified by Sheldon et al. and the criterion to classify or diagnose it was first defined by Barnes et al. and Sciubba and Brannon. Myoepithelioma accounts for less than 1 % of all salivary gland tumours, 40 % of these tumours occur in the parotid gland while 21 % occur in the minor salivary glands. A case of myoepithelioma of a minor salivary gland of the cheek is described, emphasizing the problems of the differential diagnosis. A 40-year-old female reported to the department with a complaint of a cheek bite on her right side for a few months. The physical examination showed a presence of lobulated whitish mucosa on the right buccal mucosa at the level of the occlusal plane, on palpation it revealed a non-painful mass approximately 1.5 cm in radius, mobile to bimanual palpation. An excisional biopsy was performed under local anaesthesia. Microscopic and immunohistochemistry confirmed the tumour to be a myoepithelioma of a minor salivary gland with the absence of definitive features of malignancy. Due to their infrequency and multiplicity of histopathology, myoepitheliomas present difficulties in diagnosis. Cellular varieties can be misdiagnosed as malignancies. A key to determining diagnostic criteria for myoepitheliomas is to study cellular morphology, cytoplasmic filament expression, and ultrastructural features of the tumour and apply this information to defining myoepitheliomas. Myoepitheliomas are rare tumours, utilization of immunohistochemical staining and electron microscopy are useful tools for the diagnosis of myoepitheliomas to ensure proper treatment and follow-up. •Myoepithelioma of minor salivary gland•Buccal fat pad reconstruction•Electron microscopy and Immunohistochemistry•Benign salivary gland pathology