Evaluating the Sputum Bacteriological Profile of Lower Respiratory Tract Infections With Bartlett Score Analysis in a Tertiary Care Hospital in Southern Karnataka

• Published in: Curēus (Palo Alto, CA) CA), 2024-06, Vol.16 (6), p.e61924
• Main Authors: Mahale, Rashmi P, Darpan Sheth, Param, Murthy, Neetha S
• Format: Article
• Language: English
• Subjects: Age groups; Antibiotics; Bacteria; Gram-negative bacteria; Gram-positive bacteria; Hospitals; Infections; Infectious Disease; Integrative/Complementary Medicine; Laboratories; Neutrophils; Organisms; Pathogens; Pneumonia; Quality Improvement
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.61924

Lower respiratory tract infections (LRTIs) are one of the most commonly encountered infections with significant mortality and morbidity. Sputum is the most frequently obtained sample for LRTI diagnosis. However, sputum samples carry the risk of being non-representative due to the risk of contamination with oral colonizers. To overcome the dilemma with respect to representative sampling, the use of a scoring system such as the Bartlett scoring system is emphasized. This study probes the bacterial profile of sputum samples among patients presenting with LRTIs and their antibiotic susceptibility profile in relation to the Bartlett scoring system. Retrospective data for a period of three years, comprising 4960 sputum samples from patients presenting with LRTI, were collected to study the bacterial profile and antibiogram in comparison with the sputum quality analyzed by the Bartlett scoring system. Out of the 4960 sputum samples analyzed from patients with LRTI, 31.18% yielded the growth of bacterial pathogens, and 98.64% of the sputum samples yielding pathogenic growth had a significant Bartlett score. Sputum samples are non-invasive representative samples of lower airway infective pathologies. Sputum quality assessment by Bartlett scoring serves as a proxy marker to rule out respiratory colonization and aid culture-based diagnosis.