Cardiac amyloidosis red flags: What all the cardiologist have to know

Cardiac amyloidosis is becoming increasingly important among cardiologist and an early diagnosis is very important. Amyloidosis is a systemic disease and many cardiac and extracardiac elements (red flags) should raise the suspicion of the disease. Electrocardiographic and imaging techniques (such as...

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Bibliographic Details
Published in:International journal of cardiology. Cardiovascular risk and prevention 2024-06, Vol.21, p.200271, Article 200271
Main Authors: Maloberti, Alessandro, Ciampi, Claudio, Politi, Francesco, Fabbri, Saverio, Musca, Francesco, Giannattasio, Cristina
Format: Article
Language:English
Subjects:
Cardiac amyloidosis
ITACARE Society Proceeding
Red flag
Transthyretin
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Summary:Cardiac amyloidosis is becoming increasingly important among cardiologist and an early diagnosis is very important. Amyloidosis is a systemic disease and many cardiac and extracardiac elements (red flags) should raise the suspicion of the disease. Electrocardiographic and imaging techniques (such as echocardiography, cardiac magnetic resonance and scintigraphy) are useful tools to make a diagnosis together with the presence of orthopedic issues, peripheral neuropathy or plasma cell dyscrasia. Cardiac amyloidosis is also often associated with valvular disorder, heart failure or cardiomyopathy. Red flags are crucial to raise suspicion and reach an early diagnosis, in order to start a targeted treatment strategy that could change the patient's outcome. Indeed, in the last years four new drugs were approved to treat transthyretin amyloidosis.
ISSN:2772-4875
2772-4875
DOI:10.1016/j.ijcrp.2024.200271