Assessment of the Effect of Meaningful Occupations on Motivation by Orbitofrontal Cortex Activation Using Near-Infrared Spectroscopy

• Published in: Curēus (Palo Alto, CA) CA), 2024-08, Vol.16 (8), p.e66541
• Main Authors: Ishikawa, Shintaro, Fujii, Keisuke, Kunoh, Kenta, Kimura, Daisuke
• Format: Article
• Language: English
• Subjects: Brain research; Decision making; Design; Hemoglobin; Neurology; Occupational therapy; Physical Medicine & Rehabilitation; Spectrum analysis; Statistical analysis
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.66541

Meaningful occupations are those perceived as important by an individual. Research on meaningful occupations relies on subjective data and requires qualitative inquiries. Therefore, assessing the meaning of occupations using objective methods is challenging. As orbitofrontal cortex (OFC) activation is part of the reward system network involved in motivation, it could aid in assessing the meaning of occupations. We aimed to investigate the effect of meaningful occupations on motivation by measuring OFC activation using near-infrared spectroscopy (NIRS). Eight young and healthy participants were enrolled in this study. The occupation was set as "cooking," and its importance was confirmed using the Canadian Occupational Performance Measure (COPM). NIRS was performed using an OEG-16 (Spectareteh Inc.). The target task involved watching a cooking video, while the control task consisted of looking at a "+" sign on a blank sheet of paper. OFC activation was measured based on changes in oxygenated hemoglobin (oxy-Hb) concentration using a block design. Participants with COPM scores of eight or more were classified into the "meaningful occupation performance" group, while those with scores of seven or lower were classified into the "meaningful occupation non-performance" group. Changes in oxy-Hb concentrations between the two groups were compared using the Mann-Whitney U test. Four participants were assigned to the meaningful occupation group (frequency of implementation: various times per week for all participants), and four participants were assigned to the meaningful occupation non-performance group (frequency of implementation: various times per week for one participant, various times per month for one participant, and various times per year for two participants). Statistical analysis revealed significant differences in the changes in the oxy-Hb concentration in the left and bilateral OFC. This study suggests that it is important to focus on meaningful occupations that individuals consider important in order to activate the reward system and increase motivation.