Axial length association with corneoscleral sagittal height and scleral asymmetry

• Published in: Ophthalmic & physiological optics 2025-01, Vol.45 (1), p.152-159
• Main Authors: Martínez‐Plaza, Elena, López‐de la Rosa, Alberto, Molina‐Martín, Ainhoa, Bataille, Laurent, Piñero, David P.
• Format: Article
• Language: English
• Subjects: Adult; Asymmetry; axial length; Axial Length, Eye - anatomy & histology; Axial Length, Eye - diagnostic imaging; Biometry - methods; Cornea; Cornea - anatomy & histology; Cornea - diagnostic imaging; Corneal Topography - methods; corneoscleral profile; Correlation analysis; eye surface profiler; Female; Healthy Volunteers; Humans; Male; Middle Aged; Myopia; Original; Regression analysis; sagittal height; sclera; Sclera - anatomy & histology; Young Adult
• ISSN: 0275-5408; 1475-1313; 1475-1313
• DOI: 10.1111/opo.13402

Purpose To determine how corneoscleral geometry changes with axial length and to assess the usefulness of including the sagittal configuration of the anterior segment when predicting the axial length. Methods An observational study was performed including 96 healthy subjects (96 eyes). Axial length was calculated from optical biometry (IOL Master 500). Corneal curvature and scleral sagittal height parameters at 13, 14 and 15 mm were obtained automatically using corneoscleral topography (eye surface profiler; ESP). In addition, corneal and scleral sagittal heights at numerous locations (21 radii: 0–10 mm from the corneal apex at 12 angles: 0–330°) were calculated using the raw height data extracted from the ESP. The relationships between axial length and the study parameters were analysed using Pearson correlation analysis. The equations for the prediction of axial length were obtained by fitting multiple linear regression models. Results The temporal‐nasal scleral asymmetry at 13‐, 14‐ and 15‐mm chord lengths was significantly correlated with axial length (r2 ≤ 0.26; p