Configurational entropy of native proteins

Simulations of the residual configurational entropy of a protein in the native state suggest that it is nearly an order of magnitude larger than the entropy of denaturation. The implications of this result are discussed.

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Published in:Biophysical journal 1987-12, Vol.52 (6), p.1083-1085
Main Authors: Karplus, M., Ichiye, T., Pettitt, B.M.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Mathematics
Molecular biophysics
Protein Conformation
Proteins
Structure in molecular biology
Thermodynamics
Tridimensional structure
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container_issue 6
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container_title Biophysical journal
container_volume 52
creator Karplus, M.
Ichiye, T.
Pettitt, B.M.
description Simulations of the residual configurational entropy of a protein in the native state suggest that it is nearly an order of magnitude larger than the entropy of denaturation. The implications of this result are discussed.
doi_str_mv 10.1016/S0006-3495(87)83303-9
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source Open Access: PubMed Central
subjects Biological and medical sciences
Fundamental and applied biological sciences. Psychology
Mathematics
Molecular biophysics
Protein Conformation
Proteins
Structure in molecular biology
Thermodynamics
Tridimensional structure
title Configurational entropy of native proteins
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