Imaging of the brain in acute ischaemic stroke: comparison of computed tomography and magnetic resonance diffusion-weighted imaging

Background and objectives: Controversy exists about the optimal imaging technique in acute stroke. It was hypothesised that CT is comparable with DWI, when both are read systematically using quantitative scoring. Methods: Ischaemic stroke patients who had CT within six hours and DWI within seven hou...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 2005-11, Vol.76 (11), p.1528-1533
Main Authors: Barber, P A, Hill, M D, Eliasziw, M, Demchuk, A M, Pexman, J H W, Hudon, M E, Tomanek, A, Frayne, R, Buchan, A M
Format: Article
Language:English
Subjects:
Aged
Alberta Stroke Programme Early Computed Tomography Score
ASPECTS
Biological and medical sciences
Brain - blood supply
Brain - diagnostic imaging
Brain - pathology
Brain Ischemia - diagnosis
Brain Ischemia - epidemiology
Cerebrovascular Circulation - physiology
computed tomography
Diffusion
Diffusion Magnetic Resonance Imaging
diffusion weighted imaging
DWI
early ischaemic changes
EIC
Female
FLAIR
fluid attenuated inversion recovery
Heart attacks
Humans
Investigative techniques, diagnostic techniques (general aspects)
ischaemic stroke
magnetic resonance angiography
magnetic resonance imaging
Male
Medical imaging
Medical sciences
Middle Aged
modified Rankin scale
MRA
MRI
mRS
National Institutes of Health Stroke Scale
Nervous system
Neurology
NIHSS
NMR
Nuclear magnetic resonance
Observer Variation
Prospective Studies
Radiodiagnosis. Nmr imagery. Nmr spectrometry
Sensitivity and Specificity
Severity of Illness Index
Stroke
thrombolysis
tissue plasminogen activator
Tomography, X-Ray Computed
tPA
Traumatic brain injury
Vascular diseases and vascular malformations of the nervous system
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Summary:Background and objectives: Controversy exists about the optimal imaging technique in acute stroke. It was hypothesised that CT is comparable with DWI, when both are read systematically using quantitative scoring. Methods: Ischaemic stroke patients who had CT within six hours and DWI within seven hours of onset were included. Five readers used a quantitative scoring system (ASPECTS) to read the baseline (b) and follow up CT and DWI. Use of MRI in acute stroke was also assessed in patients treated with tissue plasminogen activator (tPA) by prospectively recording reasons for exclusion. Patients were followed clinically at three months. Results: bDWI and bCT were available for 100 consecutive patients (admission median NIHSS = 9). The mean bDWI and bCT ASPECTS were positively related (p
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.2004.059261