CARCINOMA OF THE LARYNX: RESULTS OF THERAPY

Prognosis of laryngeal carcinoma varies considerably, depending on its site and stage of development. In the past, laryngectomy was considered the treatment of choice for all but very early lesions. Results of therapy and five-year survival rates were relatively good, but the patient deprived of his...

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Bibliographic Details
Published in:Canadian Medical Association journal 1964-03, Vol.90 (13), p.757-761
Main Author: BRYCE, D P
Format: Article
Language:English
Subjects:
Carcinoma
Combined Modality Therapy
Humans
Laryngeal Neoplasms
Laryngectomy
Larynx
Larynx, Artificial
Neoplasms - epidemiology
Neoplasms - radiotherapy
Old Medline
Original
Pharyngeal Neoplasms
Prognosis
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Summary:Prognosis of laryngeal carcinoma varies considerably, depending on its site and stage of development. In the past, laryngectomy was considered the treatment of choice for all but very early lesions. Results of therapy and five-year survival rates were relatively good, but the patient deprived of his larynx frequently presented difficulties in rehabilitation.Recent advances in radiotherapy techniques have permitted treatment of a greater proportion of patients with laryngeal carcinoma by this means, with encouraging results. Results of a survey in the Toronto area suggest that radiotherapy should be used as primary treatment in early and intermediate stages of the disease; radical excision combined with radiotherapy is indicated for treatment failures among early cases and for those with far-advanced disease or carcinoma outside the larynx proper. With this program five-year survival rates are comparable to those achieved when laryngectomy is the primary treatment used, and two-thirds of those who survive maintain laryngeal function.
ISSN:0008-4409