Cost effectiveness of couple counselling to enhance infant HIV-1 prevention

Data collected in the years 2001-2003 from an antenatal clinic in Nairobi, Kenya, were used to assess the benefit of couple counselling and test it as a way of increasing the uptake of interventions in the prevention of mother-to-child transmission of HIV-1. Among 2833 women enrolled, 311 (11%) rece...

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Bibliographic Details
Published in:International journal of STD & AIDS 2008-06, Vol.19 (6), p.406-409
Main Authors: John, Francis N, Farquhar, Carey, Kiarie, James N, Kabura, Marjory N, John-Stewart, Grace C
Format: Article
Language:English
Subjects:
AIDS Serodiagnosis - economics
Anti-HIV Agents - administration & dosage
Anti-HIV Agents - economics
Biological and medical sciences
Cost-Benefit Analysis
Counseling - economics
Epidemiology. Vaccinations
General aspects
Health Education
HIV Infections - diagnosis
HIV Infections - economics
HIV Infections - epidemiology
HIV Infections - prevention & control
HIV Infections - transmission
HIV Seroprevalence
HIV-1
Human immunodeficiency virus 1
Human viral diseases
Humans
Infectious Disease Transmission, Vertical - economics
Infectious Disease Transmission, Vertical - prevention & control
Infectious diseases
Medical sciences
Original
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
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Summary:Data collected in the years 2001-2003 from an antenatal clinic in Nairobi, Kenya, were used to assess the benefit of couple counselling and test it as a way of increasing the uptake of interventions in the prevention of mother-to-child transmission of HIV-1. Among 2833 women enrolled, 311 (11%) received couple pretest counselling and 2100 (74%) accepted HIV-1 testing. Among those tested 314 (15%) were HIV-1 seropositive. We incorporated these and other data from the cohort study into a spreadsheetbased model and costs associated with couple counselling were compared with individual counselling in a theoretical cohort of 10,000 women. Voluntary couple counselling and testing (VCT), although more expensive, averted a greater number of infant infections when compared with individual VCT. Cost per disability-adjusted life year was similar to that of individual VCT. Sensitivity analyses found that couple VCT was more cost-effective in scenarios with increased uptake of couple counselling and higher HIV-1 prevalence.
ISSN:0956-4624
1758-1052
DOI:10.1258/ijsa.2008.007234