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Kidney Stones Associate with Increased Risk for Myocardial Infarction
Kidney stones are a risk factor for chronic kidney disease (CKD), which, in turn, is a risk factor for myocardial infarction (MI). The objective of this study was to determine whether kidney stones associate with an increased risk for MI. We matched 4564 stone formers (1984 through 2003) on age and...
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Published in: | Journal of endourology 2010-10, Vol.21 (10), p.1641-1644 |
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container_end_page | 1644 |
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container_title | Journal of endourology |
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creator | RULE, Andrew D ROGER, Veronique L MELTON, L. Joseph BERGSTRALH, Eric J XUJIAN LI PEYSER, Patricia A KRAMBECK, Amy E LIESKE, John C |
description | Kidney stones are a risk factor for chronic kidney disease (CKD), which, in turn, is a risk factor for myocardial infarction (MI). The objective of this study was to determine whether kidney stones associate with an increased risk for MI. We matched 4564 stone formers (1984 through 2003) on age and gender with 10,860 control subjects among residents in Olmsted County, Minnesota. We identified incident MI by diagnostic codes and validated events by chart review through 2006. We used diagnostic codes to determine incidence of kidney stones and presence of comorbidities (CKD, hypertension, diabetes, obesity, dyslipidemia, gout, alcohol dependence, and tobacco use). During a mean of 9 years of follow-up, stone formers had a 38% (95% confidence interval 7 to 77%) increased risk for MI, which remained at 31% (95% confidence interval 2% to 69%) after adjustment for CKD and other comorbidities. In conclusion, kidney stone formers are at increased risk for MI, and this risk is independent of CKD and other risk factors. |
doi_str_mv | 10.1681/ASN.2010030253 |
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Joseph ; BERGSTRALH, Eric J ; XUJIAN LI ; PEYSER, Patricia A ; KRAMBECK, Amy E ; LIESKE, John C</creator><creatorcontrib>RULE, Andrew D ; ROGER, Veronique L ; MELTON, L. Joseph ; BERGSTRALH, Eric J ; XUJIAN LI ; PEYSER, Patricia A ; KRAMBECK, Amy E ; LIESKE, John C</creatorcontrib><description>Kidney stones are a risk factor for chronic kidney disease (CKD), which, in turn, is a risk factor for myocardial infarction (MI). The objective of this study was to determine whether kidney stones associate with an increased risk for MI. We matched 4564 stone formers (1984 through 2003) on age and gender with 10,860 control subjects among residents in Olmsted County, Minnesota. We identified incident MI by diagnostic codes and validated events by chart review through 2006. We used diagnostic codes to determine incidence of kidney stones and presence of comorbidities (CKD, hypertension, diabetes, obesity, dyslipidemia, gout, alcohol dependence, and tobacco use). During a mean of 9 years of follow-up, stone formers had a 38% (95% confidence interval 7 to 77%) increased risk for MI, which remained at 31% (95% confidence interval 2% to 69%) after adjustment for CKD and other comorbidities. In conclusion, kidney stone formers are at increased risk for MI, and this risk is independent of CKD and other risk factors.</description><identifier>ISSN: 1046-6673</identifier><identifier>ISSN: 0892-7790</identifier><identifier>EISSN: 1533-3450</identifier><identifier>DOI: 10.1681/ASN.2010030253</identifier><identifier>PMID: 20616170</identifier><identifier>CODEN: JASNEU</identifier><language>eng</language><publisher>Washington, DC: American Society of Nephrology</publisher><subject>Adult ; Biological and medical sciences ; Brief Communication ; Cardiology. Vascular system ; Case-Control Studies ; Complications and side effects ; Coronary heart disease ; Female ; Heart ; Heart attack ; Humans ; Kidney Calculi - complications ; Kidney Calculi - epidemiology ; Kidney stones ; Male ; Medical sciences ; Middle Aged ; Minnesota - epidemiology ; Myocardial Infarction - epidemiology ; Myocardial Infarction - etiology ; Nephrology. Urinary tract diseases ; Risk Factors ; Urinary lithiasis</subject><ispartof>Journal of endourology, 2010-10, Vol.21 (10), p.1641-1644</ispartof><rights>2015 INIST-CNRS</rights><rights>COPYRIGHT 2011 Mary Ann Liebert, Inc.</rights><rights>Copyright © 2010 by the American Society of Nephrology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c486t-e8e15c53037b7f4f77d65a1fbf99336d8b02b25e5e0d21d6e000ad44117ead8b3</citedby><cites>FETCH-LOGICAL-c486t-e8e15c53037b7f4f77d65a1fbf99336d8b02b25e5e0d21d6e000ad44117ead8b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013539/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013539/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23285312$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20616170$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RULE, Andrew D</creatorcontrib><creatorcontrib>ROGER, Veronique L</creatorcontrib><creatorcontrib>MELTON, L. Joseph</creatorcontrib><creatorcontrib>BERGSTRALH, Eric J</creatorcontrib><creatorcontrib>XUJIAN LI</creatorcontrib><creatorcontrib>PEYSER, Patricia A</creatorcontrib><creatorcontrib>KRAMBECK, Amy E</creatorcontrib><creatorcontrib>LIESKE, John C</creatorcontrib><title>Kidney Stones Associate with Increased Risk for Myocardial Infarction</title><title>Journal of endourology</title><addtitle>J Am Soc Nephrol</addtitle><description>Kidney stones are a risk factor for chronic kidney disease (CKD), which, in turn, is a risk factor for myocardial infarction (MI). The objective of this study was to determine whether kidney stones associate with an increased risk for MI. We matched 4564 stone formers (1984 through 2003) on age and gender with 10,860 control subjects among residents in Olmsted County, Minnesota. We identified incident MI by diagnostic codes and validated events by chart review through 2006. We used diagnostic codes to determine incidence of kidney stones and presence of comorbidities (CKD, hypertension, diabetes, obesity, dyslipidemia, gout, alcohol dependence, and tobacco use). During a mean of 9 years of follow-up, stone formers had a 38% (95% confidence interval 7 to 77%) increased risk for MI, which remained at 31% (95% confidence interval 2% to 69%) after adjustment for CKD and other comorbidities. In conclusion, kidney stone formers are at increased risk for MI, and this risk is independent of CKD and other risk factors.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Brief Communication</subject><subject>Cardiology. Vascular system</subject><subject>Case-Control Studies</subject><subject>Complications and side effects</subject><subject>Coronary heart disease</subject><subject>Female</subject><subject>Heart</subject><subject>Heart attack</subject><subject>Humans</subject><subject>Kidney Calculi - complications</subject><subject>Kidney Calculi - epidemiology</subject><subject>Kidney stones</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Minnesota - epidemiology</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Myocardial Infarction - etiology</subject><subject>Nephrology. 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Joseph ; BERGSTRALH, Eric J ; XUJIAN LI ; PEYSER, Patricia A ; KRAMBECK, Amy E ; LIESKE, John C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c486t-e8e15c53037b7f4f77d65a1fbf99336d8b02b25e5e0d21d6e000ad44117ead8b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Brief Communication</topic><topic>Cardiology. Vascular system</topic><topic>Case-Control Studies</topic><topic>Complications and side effects</topic><topic>Coronary heart disease</topic><topic>Female</topic><topic>Heart</topic><topic>Heart attack</topic><topic>Humans</topic><topic>Kidney Calculi - complications</topic><topic>Kidney Calculi - epidemiology</topic><topic>Kidney stones</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Minnesota - epidemiology</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Myocardial Infarction - etiology</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Risk Factors</topic><topic>Urinary lithiasis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RULE, Andrew D</creatorcontrib><creatorcontrib>ROGER, Veronique L</creatorcontrib><creatorcontrib>MELTON, L. Joseph</creatorcontrib><creatorcontrib>BERGSTRALH, Eric J</creatorcontrib><creatorcontrib>XUJIAN LI</creatorcontrib><creatorcontrib>PEYSER, Patricia A</creatorcontrib><creatorcontrib>KRAMBECK, Amy E</creatorcontrib><creatorcontrib>LIESKE, John C</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of endourology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RULE, Andrew D</au><au>ROGER, Veronique L</au><au>MELTON, L. Joseph</au><au>BERGSTRALH, Eric J</au><au>XUJIAN LI</au><au>PEYSER, Patricia A</au><au>KRAMBECK, Amy E</au><au>LIESKE, John C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Kidney Stones Associate with Increased Risk for Myocardial Infarction</atitle><jtitle>Journal of endourology</jtitle><addtitle>J Am Soc Nephrol</addtitle><date>2010-10-01</date><risdate>2010</risdate><volume>21</volume><issue>10</issue><spage>1641</spage><epage>1644</epage><pages>1641-1644</pages><issn>1046-6673</issn><issn>0892-7790</issn><eissn>1533-3450</eissn><coden>JASNEU</coden><abstract>Kidney stones are a risk factor for chronic kidney disease (CKD), which, in turn, is a risk factor for myocardial infarction (MI). The objective of this study was to determine whether kidney stones associate with an increased risk for MI. We matched 4564 stone formers (1984 through 2003) on age and gender with 10,860 control subjects among residents in Olmsted County, Minnesota. We identified incident MI by diagnostic codes and validated events by chart review through 2006. We used diagnostic codes to determine incidence of kidney stones and presence of comorbidities (CKD, hypertension, diabetes, obesity, dyslipidemia, gout, alcohol dependence, and tobacco use). During a mean of 9 years of follow-up, stone formers had a 38% (95% confidence interval 7 to 77%) increased risk for MI, which remained at 31% (95% confidence interval 2% to 69%) after adjustment for CKD and other comorbidities. In conclusion, kidney stone formers are at increased risk for MI, and this risk is independent of CKD and other risk factors.</abstract><cop>Washington, DC</cop><pub>American Society of Nephrology</pub><pmid>20616170</pmid><doi>10.1681/ASN.2010030253</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Biological and medical sciences Brief Communication Cardiology. Vascular system Case-Control Studies Complications and side effects Coronary heart disease Female Heart Heart attack Humans Kidney Calculi - complications Kidney Calculi - epidemiology Kidney stones Male Medical sciences Middle Aged Minnesota - epidemiology Myocardial Infarction - epidemiology Myocardial Infarction - etiology Nephrology. Urinary tract diseases Risk Factors Urinary lithiasis |
title | Kidney Stones Associate with Increased Risk for Myocardial Infarction |
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