Computed Tomography in Color: NanoK-Enhanced Spectral CT Molecular Imaging

Multicolored imaging: A new class of molecular imaging agent has been developed based on low‐molecular‐weight organically soluble bismuth to detect and quantify intraluminal fibrin presented by ruptured plaque in the context of computed tomography angiograms without calcium interference.

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Bibliographic Details
Published in:Angewandte Chemie (International ed.) 2010-12, Vol.49 (50), p.9635-9639
Main Authors: Pan, Dipanjan, Roessl, Ewald, Schlomka, Jens-Peter, Caruthers, Shelton D, Senpan, Angana, Scott, Mike J, Allen, John S, Zhang, Huiying, Hu, Grace, Gaffney, Patrick J, Choi, Eric T, Rasche, Volker, Wickline, Samuel A, Proksa, Roland, Lanza, Gregory M
Format: Article
Language:English
Subjects:
Animals
bismuth
Bismuth - chemistry
Colloids - chemistry
Color
computed tomography
contrast agents
Contrast Media - chemistry
Fibrin - analysis
Humans
Male
Mice
Mice, Inbred BALB C
molecular imaging
nanocolloids
Nanoparticles - chemistry
Rabbits
Thrombosis - diagnostic imaging
Tomography, X-Ray Computed - methods
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Description
Summary:Multicolored imaging: A new class of molecular imaging agent has been developed based on low‐molecular‐weight organically soluble bismuth to detect and quantify intraluminal fibrin presented by ruptured plaque in the context of computed tomography angiograms without calcium interference.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201005657