In vivo assessment of anterior compartment compliance and its relation to prolapse

Introduction and hypothesis The objective of the study was to compare anterior compartment compliance between women with and without pelvic organ prolapse and to explore factors determining the extent of anterior compartment prolapse. Methods Ten women with normal pelvic support and nine with anteri...

Full description

Saved in:
Bibliographic Details
Published in:International Urogynecology Journal 2010-09, Vol.21 (9), p.1111-1115
Main Authors: Hsu, Yvonne, Chen, Luyun, Tumbarello, Julie, Ashton-Miller, James A., DeLancey, John O. L.
Format: Article
Language:English
Subjects:
Abdominal Cavity - physiopathology
Biomechanical Phenomena
Compliance - physiology
Female
Follow-Up Studies
Gynecology
Humans
Magnetic Resonance Imaging
Medicine
Medicine & Public Health
Middle Aged
Original Article
Pelvic Organ Prolapse - diagnosis
Pelvic Organ Prolapse - physiopathology
Pressure
Rest
Retrospective Studies
Urology
Vagina - physiopathology
Valsalva Maneuver
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction and hypothesis The objective of the study was to compare anterior compartment compliance between women with and without pelvic organ prolapse and to explore factors determining the extent of anterior compartment prolapse. Methods Ten women with normal pelvic support and nine with anterior compartment prolapse were analyzed. Abdominal pressure was measured during Valsalva and simultaneous midsagittal dynamic MR imaging. The distance between the most dependent anterior vaginal wall point and a previously determined average nulliparous anterior vaginal wall point was measured. A best-fit line was determined when anterior vaginal wall displacement was plotted relative to abdominal pressure. The slope of this line is a measure of anterior compartment compliance. Multivariate analyses and t tests were performed. Results Mean compliance (centimeters per centimeter of water) was higher for cases [0.05 ± 0.006 standard error of the mean (SEM)] than controls (0.03 ± .007, p  = 0.039). Degree of anterior compartment prolapse correlated best with compliance ( R 2  = 0.75, p  
ISSN:0937-3462
1433-3023
DOI:10.1007/s00192-010-1154-9