Pt-Catalyzed Pentannulations from In Situ Generated Metallo−Carbenoids Utilizing Propargylic Esters

A highly selective and efficient Pt-catalyzed pentannulation reaction beginning from propargylic esters is described. The key to this reaction is the use of a PtCl2(PPh3)2/PhIO catalyst combination that allows the in situ generation of Pt−carbenoid intermediates, which lead to good yields (61−84%) o...

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Published in:Journal of the American Chemical Society 2005-09, Vol.127 (36), p.12468-12469
Main Authors: Bhanu Prasad, B. A, Yoshimoto, Francis K, Sarpong, Richmond
Format: Article
Language:English
Subjects:
Alkynes - chemistry
Catalysis
Chemistry
Cyclization
Esters - chemical synthesis
Esters - chemistry
Exact sciences and technology
Kinetics and mechanisms
Molecular Structure
Organic chemistry
Organoplatinum Compounds - chemistry
Platinum - chemistry
Reactivity and mechanisms
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cited_by cdi_FETCH-LOGICAL-a537t-b8d6ef3cdb15fb4c00341aff1b8e3af95b764de46bac9a97ead9ec1ddec930d23
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container_issue 36
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container_title Journal of the American Chemical Society
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creator Bhanu Prasad, B. A
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description A highly selective and efficient Pt-catalyzed pentannulation reaction beginning from propargylic esters is described. The key to this reaction is the use of a PtCl2(PPh3)2/PhIO catalyst combination that allows the in situ generation of Pt−carbenoid intermediates, which lead to good yields (61−84%) of the desired pentannulated compounds.
doi_str_mv 10.1021/ja053192c
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source American Chemical Society:Jisc Collections:American Chemical Society Read & Publish Agreement 2022-2024 (Reading list)
subjects Alkynes - chemistry
Catalysis
Chemistry
Cyclization
Esters - chemical synthesis
Esters - chemistry
Exact sciences and technology
Kinetics and mechanisms
Molecular Structure
Organic chemistry
Organoplatinum Compounds - chemistry
Platinum - chemistry
Reactivity and mechanisms
title Pt-Catalyzed Pentannulations from In Situ Generated Metallo−Carbenoids Utilizing Propargylic Esters
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