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Campylobacter Peritonitis Complicating Peritoneal Dialysis: A Review of 12 Consecutive Cases
♦ Background: Peritoneal dialysis-associated peritonitis secondary to Campylobacter organisms is uncommon. Few studies have assessed either treatment or clinical outcomes. ♦ Methods: We reviewed all Campylobacter peritonitis episodes occurring in a single dialysis unit from 1994 to 2011. ♦ Results:...
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Published in: | Peritoneal dialysis international 2013-03, Vol.33 (2), p.189-194 |
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Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | ♦
Background:
Peritoneal dialysis-associated peritonitis secondary to
Campylobacter
organisms is uncommon. Few studies have assessed either treatment or clinical outcomes.
♦
Methods:
We reviewed all
Campylobacter
peritonitis episodes occurring in a single dialysis unit from 1994 to 2011.
♦
Results:
During the study period, 12 episodes of
Campylobacter
peritonitis (0.45% of all peritonitis episodes) were recorded. Diarrhea was uncommon (8.3%). The overall primary response rate was 91.7%; the complete cure rate was 75.0%. Among 6 patients who failed to respond to standard antibiotics by day 5, all improved after administration of an oral macrolide (erythromycin or clarithromycin). Of those 6 patients, 5 experienced a complete cure, and 1 patient experienced relapse of culture-negative peritonitis. No patient required Tenckhoff catheter removal or temporary hemodialysis support. The 30-day mortality was 0%.
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Conclusions: Campylobacter
peritonitis might not respond to first-line conventional antibiotics, and an oral macrolide is recommended if
Campylobacter
is confirmed. The findings from our analysis do not support the use of fluoroquinolone, which is associated with a high resistance rate. |
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ISSN: | 0896-8608 1718-4304 |
DOI: | 10.3747/pdi.2011.00323 |