Satiety, but not total PYY, Is increased with continuous and intermittent exercise

• Published in: Obesity (Silver Spring, Md.) Md.), 2013-10, Vol.21 (10), p.2014-2020
• Main Authors: Holmstrup, M. E., Fairchild, T. J., Keslacy, S., Weinstock, R. S., Kanaley, J. A.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Appetite - physiology; Blood Glucose - metabolism; Blood pressure; Body mass index; Cholesterol; Cross-Over Studies; Exercise; Exercise - physiology; Female; Food; Humans; Insulin; Insulin - blood; Male; Obesity; Obesity - blood; Obesity - therapy; Peptide YY - blood; Satiation - physiology; Satiety Response - physiology; Weight control; Young Adult
• ISSN: 1930-7381; 1930-739X
• DOI: 10.1002/oby.20335

Objective This study determined the hormonal and subjective appetite responses to exercise (1‐h continuous versus intermittent exercise throughout the day) in obese individuals. Design and Methods Eleven obese subjects (>30 kg/m2) underwent three 12‐h study days: control condition [sedentary behavior (SED)], continuous exercise condition [(EX) 1‐h exercise], and intermittent exercise condition [(INT) 12 hourly, 5‐min bouts]. Blood samples (every 10 min) were measured for serum insulin and total peptide YY (PYY) concentrations, with ratings of appetite (visual analog scale [VAS): every 20 min]. Both total area under the curve (AUC), and subjective appetite ratings were calculated. Results No differences were observed in total PYY AUC between conditions, but hunger was reduced with INT (INT < EX; P < 0.05), and satiety was increased with both SED and INT conditions (INT > EX and SED > EX; P < 0.05). A correlation existed between the change in total PYY and insulin levels (r = −0.81; P < 0.05), and total PYY and satiety (r = 0.80; P < 0.05) with the EX condition, not the SED and INT conditions. Conclusions The total PYY response to meals is not altered over the course of a 12‐h day with either intermittent or continuous exercise; however, intermittent exercise increased satiety and reduced hunger to a greater extent than continuous exercise in obese individuals.