Systemic Hypertension Requiring Treatment in the Neonatal Intensive Care Unit

Objectives To determine the difference in the risk factors for systemic hypertension in preterm and term infants in the neonatal intensive care unit (NICU). Study design Data were collected from an existing database of NICU children and confirmed by chart review. Systemic hypertension was defined wh...

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Bibliographic Details
Published in:The Journal of pediatrics 2013-07, Vol.163 (1), p.84-88
Main Authors: Sahu, Raj, DO, Pannu, Hariyadarshi, PhD, Yu, Robert, Shete, Sanjay, PhD, Bricker, John T., MD, Gupta-Malhotra, Monesha, MBBS
Format: Article
Language:English
Subjects:
bronchopulmonary dysplasia
children
diastolic blood pressure
drug therapy
Female
Humans
hypertension
Hypertension - drug therapy
hypertrophy
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - drug therapy
infants
Intensive Care Units, Neonatal
Intensive Care, Neonatal
Male
mortality
patent ductus arteriosus
Pediatrics
pregnancy
Retrospective Studies
Risk Factors
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Summary:Objectives To determine the difference in the risk factors for systemic hypertension in preterm and term infants in the neonatal intensive care unit (NICU). Study design Data were collected from an existing database of NICU children and confirmed by chart review. Systemic hypertension was defined when 3 separate measurements of systolic and/or diastolic blood pressure were >95th percentile and an antihypertensive medication was administered for >2 weeks in the NICU. Results Of 4203 infants, we identified 53 (1.3%) with treated hypertension, of whom 74% were preterm, 11% required surgical intervention, and 85% required medications on discharge. The presence of a patent ductus arteriosus, umbilical catheterization, left ventricular hypertrophy, hypertensive medication at discharge, and mortality was similar between the term and preterm infants. The major risk factors for preterm infants, especially those
ISSN:0022-3476
1097-6833
DOI:10.1016/j.jpeds.2012.12.074