Focal nodular hyperplasia: characterisation at gadoxetic acid-enhanced MRI and diffusion-weighted MRI

• Published in: British journal of radiology 2013-08, Vol.86 (1028), p.20130299-20130299
• Main Authors: An, H S, Park, H S, Kim, Y J, Jung, S I, Jeon, H J
• Format: Article
• Language: English
• Subjects: Adult; Aged; Contrast Media; Diffusion Magnetic Resonance Imaging; Female; Focal Nodular Hyperplasia - diagnosis; Gadolinium DTPA; Humans; Magnetic Resonance Imaging - methods; Male; Middle Aged; Retrospective Studies; Young Adult
• ISSN: 0007-1285; 1748-880X
• DOI: 10.1259/bjr.20130299

The aim of this study was to assess the enhancement patterns of hepatic focal nodular hyperplasia (FNH) on gadoxetic acid-enhanced MRI and diffusion-weighted (DW) MRI. This retrospective study had institutional review board approval. Gadoxetic acid-enhanced and DW MR images were evaluated in 23 patients with 30 FNHs (26 histologically proven and 4 radiologically diagnosed). The lesion enhancement patterns of the hepatobiliary phase images were classified as heterogeneous or homogeneous signal intensity (SI), and as dominantly high/iso or low SI compared with those of adjacent liver parenchyma. Heterogeneous (any) SI lesions and homogeneous low SI lesions were categorised into the fibrosis group, whereas homogeneous high/iso SI lesions were categorised into the non-fibrosis group. Additionally, lesion SI on T2 weighted images, DW images and apparent diffusion coefficient (ADC) values were compared between the two groups. The lesions showed heterogeneous high/iso SI (n=16), heterogeneous low SI (n=5), homogeneous high/iso SI (n=7) or homogeneous low SI (n=2) at the hepatobiliary phase MR images. The fibrosis group lesions were more likely to show high SI on DW images and T2 weighted images compared with those in the non-fibrosis group (p