Characterizing mild cognitive impairment in incident Parkinson disease: The ICICLE-PD Study

OBJECTIVE:To describe the frequency of mild cognitive impairment (MCI) in Parkinson disease (PD) in a cohort of newly diagnosed incident PD cases and the associations with a panel of biomarkers. METHODS:Between June 2009 and December 2011, 219 subjects with PD and 99 age-matched controls participate...

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Published in:	Neurology 2014-01, Vol.82 (4), p.308-316
Main Authors:	Yarnall, Alison J., Breen, David P., Duncan, Gordon W., Khoo, Tien K., Coleman, Shirley Y., Firbank, Michael J., Nombela, Cristina, Winder-Rhodes, Sophie, Evans, Jonathan R., Rowe, James B., Mollenhauer, Brit, Kruse, Niels, Hudson, Gavin, Chinnery, Patrick F., O’Brien, John T., Robbins, Trevor W., Wesnes, Keith, Brooks, David J., Barker, Roger A., Burn, David J.
Format:	Article
Language:	English
Subjects:	Aged Aged, 80 and over Amyloid beta-Peptides - cerebrospinal fluid Biological and medical sciences Case-Control Studies Cognitive Dysfunction - cerebrospinal fluid Cognitive Dysfunction - diagnosis Cognitive Dysfunction - etiology Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Geriatrics Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Humans Intermediate Filament Proteins - cerebrospinal fluid Male Medical sciences Middle Aged Nervous system (semeiology, syndromes) Nervous system as a whole Neurology Neuropsychological Tests Parkinson Disease - epidemiology Peptide Fragments - cerebrospinal fluid Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Retrospective Studies Severity of Illness Index tau Proteins - cerebrospinal fluid
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