From urothelial signalling to experiencing a sensation related to the urinary bladder

The mechanisms underlying bladder sensation and the way we experience sensations during normal voiding and in pathology is complex and not well understood. During storage and emptying, mechanical changes occurring in number of cell types within the bladder wall (i.e. the uroepithelium and bladder af...

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Bibliographic Details
Published in:Acta Physiologica 2013-01, Vol.207 (1), p.34-39
Main Authors: Birder, L., Wyndaele, J.-J.
Format: Article
Language:English
Subjects:
Afferent Pathways - physiology
afferents
Animals
Bladder
Excretory system
Humans
sensation
Sensation - physiology
Signal Transduction - physiology
Urinary Bladder - innervation
Urinary Bladder - physiology
urothelium
Urothelium - innervation
Urothelium - physiology
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Summary:The mechanisms underlying bladder sensation and the way we experience sensations during normal voiding and in pathology is complex and not well understood. During storage and emptying, mechanical changes occurring in number of cell types within the bladder wall (i.e. the uroepithelium and bladder afferents) can have a major influence on our sensory systems. In this review, we discuss bladder sensation with a focus on coding events in the periphery.
ISSN:1748-1708
1748-1716
DOI:10.1111/apha.12011