A Novel Function for BRCA1 In Crosslink Repair

In this issue of Molecular Cell, Bunting et al. (2012) provide new evidence that BRCA1 plays an important role in DNA interstrand crosslink repair that is distinct from its established function in promoting DNA end resection during homologous recombination.

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Bibliographic Details
Published in:Molecular cell 2012-04, Vol.46 (2), p.111-112
Main Authors: Long, David T., Walter, Johannes C.
Format: Article
Language:English
Subjects:
DNA
homologous recombination
resection
tumor suppressor proteins
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Description
Summary:In this issue of Molecular Cell, Bunting et al. (2012) provide new evidence that BRCA1 plays an important role in DNA interstrand crosslink repair that is distinct from its established function in promoting DNA end resection during homologous recombination.
ISSN:1097-2765
1097-4164
DOI:10.1016/j.molcel.2012.04.010