Conductance modulation of charged lipid bilayer using electrolyte-gated graphene-field effect transistor

• Published in: Nanoscale research letters 2014-07, Vol.9 (1), p.371-371, Article 371
• Main Authors: Kiani, Mohammad Javad, Harun, Fauzan Khairi Che, Ahmadi, Mohammad Taghi, Rahmani, Meisam, Saeidmanesh, Mahdi, Zare, Moslem
• Format: Article
• Language: English
• Subjects: Chemistry and Materials Science; Materials Science; Molecular Medicine; Nano Idea; Nanochemistry; Nanoscale Science and Technology; Nanotechnology; Nanotechnology and Microengineering
• ISSN: 1931-7573; 1556-276X; 1556-276X
• DOI: 10.1186/1556-276X-9-371

Graphene is an attention-grabbing material in electronics, physics, chemistry, and even biology because of its unique properties such as high surface-area-to-volume ratio. Also, the ability of graphene-based materials to continuously tune charge carriers from holes to electrons makes them promising for biological applications, especially in lipid bilayer-based sensors. Furthermore, changes in charged lipid membrane properties can be electrically detected by a graphene-based electrolyte-gated graphene field effect transistor (GFET). In this paper, a monolayer graphene-based GFET with a focus on the conductance variation caused by membrane electric charges and thickness is studied. Monolayer graphene conductance as an electrical detection platform is suggested for neutral, negative, and positive electric-charged membrane. The electric charge and thickness of the lipid bilayer ( Q LP and L LP ) as a function of carrier density are proposed, and the control parameters are defined. Finally, the proposed analytical model is compared with experimental data which indicates good overall agreement.