Neuropsychological Outcomes Following Psychosocial Intervention for Depression in Parkinson’s disease

The purpose of this paper is to describe neuropsychological outcomes in people with Parkinson’s disease (PD) following their participation in an NIH-sponsored, randomized-controlled trial of cognitive-behavioral treatment for depression. Improvements in mood were associated with modest gains in verb...

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Bibliographic Details
Published in:The journal of neuropsychiatry and clinical neurosciences 2014-01, Vol.26 (1), p.57-63
Main Authors: Dobkin, Roseanne D., Tröster, Alexander I., Rubino, Jade Tiu, Allen, Lesley A., Gara, Michael A., Mark, Margery H., Menza, Matthew
Format: Article
Language:English
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Summary:The purpose of this paper is to describe neuropsychological outcomes in people with Parkinson’s disease (PD) following their participation in an NIH-sponsored, randomized-controlled trial of cognitive-behavioral treatment for depression. Improvements in mood were associated with modest gains in verbal memory and executive functioning, over the 10-week treatment period, and accounted for greater variance in neuropsychological outcomes at the end-of-treatment, than other known correlates of cognitive functioning in PD, such as disease severity, age, and education. Baseline working memory and executive skills were also associated with depression improvement over time.
ISSN:0895-0172
1545-7222
DOI:10.1176/appi.neuropsych.12120381