Human papillomavirus type‐16 positive endobronchial metastasis from uterine cervical cancer

Although the lung is the most common site of metastasis from extrapulmonary malignancies, endobronchial metastases (EBM) are relatively rare. EBM typically originate from breast, colorectal, or kidney cancer. EBM from uterine cervical cancer is relatively rare and is difficult to confirm. In this st...

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Bibliographic Details
Published in:Respirology case reports 2014-03, Vol.2 (1), p.10-12
Main Authors: Ko, Eun‐Jung, Hong, Won‐Jung, Shin, Suk‐Pyo, Shin, Sun‐Young, Heo, Jin‐Hyung, Jeong, Hye‐Cheol
Format: Article
Language:English
Subjects:
Case Reports
Cervix cancer
endobronchial metastasis
human papilloma genotyping
human papilloma virus
lung cancer
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Summary:Although the lung is the most common site of metastasis from extrapulmonary malignancies, endobronchial metastases (EBM) are relatively rare. EBM typically originate from breast, colorectal, or kidney cancer. EBM from uterine cervical cancer is relatively rare and is difficult to confirm. In this study, we report a case of EBM in a patient with previously treated uterine cervical cancer. In this case, differentiation of the EBM from primary bronchogenic carcinoma with clinical, radiological, and pathologic findings was difficult. As identical human papillomavirus (HPV)‐16 DNA was detected in both the EBM and in previously resected tissues from the prior uterine cervical cancer, the patient was diagnosed with EBM from uterine cervical cancer. HPV genotyping may aid in discriminating EBM from primary bronchogenic carcinoma in patients with uterine cervical cancer. Endobronchial metastases (EBM) from uterine cervical cancer is relatively rare and is difficult to confirm. We report a case of EBM from uterine cervical cancer, which was confirmed by human papillomavirus (HPV) genotyping. We suggest that HPV genotyping may aid in diagnosis of EBM from uterine cervical cancer.
ISSN:2051-3380
2051-3380
DOI:10.1002/rcr2.32