Sleep disturbance, depression and pain in adults with sickle cell disease

Sleep disturbance and depression are commonly encountered in primary care. In sickle cell disease, depression is associated with pain, poor treatment compliance, and lower quality of life. The prevalence of sleep disturbance and its effect upon quality of life in adults with sickle cell disease is u...

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Bibliographic Details
Published in:BMC psychiatry 2014-07, Vol.14 (1), p.207-207, Article 207
Main Authors: Wallen, Gwenyth R, Minniti, Caterina P, Krumlauf, Michael, Eckes, Ellen, Allen, Darlene, Oguhebe, Anna, Seamon, Cassie, Darbari, Deepika S, Hildesheim, Mariana, Yang, Li, Schulden, Jeffrey D, Kato, Gregory J, Taylor, 6th, James G
Format: Article
Language:English
Subjects:
Adult
Aged
Analysis
Anemia, Sickle Cell - epidemiology
Blood
Blood diseases
Care and treatment
Children & youth
Cohort Studies
Comorbidity
Complications and side effects
Cross-Sectional Studies
Depression - epidemiology
Depression, Mental
Diagnosis
Emergency medical services
Family medical history
Female
Health aspects
Humans
Male
Mental depression
Middle Aged
Mortality
Narcotics
Older people
Pain - epidemiology
Pain management
Patient compliance
Patient outcomes
Prevalence
Psychiatric Status Rating Scales
Psychiatry
Quality of Life
Review boards
Self Report
Serotonin
Sickle cell anemia
Sickle cell disease
Sleep
Sleep disorders
Sleep Wake Disorders - epidemiology
Substance abuse treatment
Suicide - psychology
United States - epidemiology
Variables
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Summary:Sleep disturbance and depression are commonly encountered in primary care. In sickle cell disease, depression is associated with pain, poor treatment compliance, and lower quality of life. The prevalence of sleep disturbance and its effect upon quality of life in adults with sickle cell disease is unknown. The goal of this study was to determine the prevalence of sleep disturbance and if it is associated with pain and depression in sickle cell disease. Three hundred twenty eight adults with sickle cell disease enrolled on the Bethesda Sickle Cell Cohort Study were assessed using the Pittsburgh Sleep Quality Index and Beck Depression Inventory II screening measures as a cross-sectional survey. Scores greater than 5 (Pittsburgh Sleep Quality Index) and 16 (Beck Depression Inventory II) defined sleep disturbance and depression, respectively. Clinical and laboratory parameters were also assessed. The mean Pittsburgh Sleep Quality Index score was 8.4 (SD ± 4.2) indicating a 71.2% prevalence of sleep disturbance. The mean Beck Depression Inventory II score was 8.0 (SD ± 8.9). Sixty five (20.6%) participants had a score indicating depression, and half of these (10.0%) had thoughts of suicide. Both Pittsburgh Sleep Quality Index and Beck Depression Inventory II scores were significantly correlated (p
ISSN:1471-244X
1471-244X
DOI:10.1186/1471-244X-14-207