HIV-Associated Neurocognitive Disorders: The Relationship of HIV Infection with Physical and Social Comorbidities

The prevalence of HIV (human immunodeficiency virus) associated neurocognitive disorders (HAND) will undoubtedly increase with the improved longevity of HIV-infected persons. HIV infection, itself, as well as multiple physiologic and psychosocial factors can contribute to cognitive impairment and ne...

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Bibliographic Details
Published in:BioMed research international 2015-01, Vol.2015 (2015), p.1-13
Main Authors: Tedaldi, Ellen M., Fischer, Tracy, Minniti, Nancy L.
Format: Article
Language:English
Subjects:
Aging - pathology
Biomarkers
Brain research
Cardiovascular Diseases - complications
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - physiopathology
Chronic illnesses
Clinical medicine
Cognition & reasoning
Cognition disorders
Cognition Disorders - epidemiology
Cognition Disorders - etiology
Cognition Disorders - physiopathology
Cognitive ability
Comorbidity
Complications and side effects
Demography
Disease
Drug therapy
Education
HIV
HIV infection
HIV Infections - complications
HIV Infections - epidemiology
HIV Infections - physiopathology
Human immunodeficiency virus
Humans
Infections
Intervention
Medicine
Memory
Mental health
Pathogenesis
Physiological aspects
Population
Prevalence
Review
Risk Factors
Sleep Wake Disorders - complications
Sleep Wake Disorders - epidemiology
Sleep Wake Disorders - physiopathology
Substance abuse treatment
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Summary:The prevalence of HIV (human immunodeficiency virus) associated neurocognitive disorders (HAND) will undoubtedly increase with the improved longevity of HIV-infected persons. HIV infection, itself, as well as multiple physiologic and psychosocial factors can contribute to cognitive impairment and neurologic complications. These comorbidities confound the diagnosis, assessment, and interventions for neurocognitive disorders. In this review, we discuss the role of several key comorbid factors that may contribute significantly to the development and progression of HIV-related neurocognitive impairment, as well as the current status of diagnostic strategies aimed at identifying HIV-infected individuals with impaired cognition and future research priorities and challenges.
ISSN:2314-6133
2314-6141
2314-6141
DOI:10.1155/2015/641913