Validation of a self-administered instrument to measure adherence to anticholinergic drugs in women with overactive bladder

• Published in: Neurourology and urodynamics 2015-06, Vol.34 (5), p.424-428
• Main Authors: Andy, Uduak U., Harvie, Heidi S., Smith, Ariana L., Propert, Kathleen J., Bogner, Hillary R., Arya, Lily A.
• Format: Article
• Language: English
• Subjects: Aged; anticholinergics; Attitude to Health; Benzhydryl Compounds - therapeutic use; Cholinergic Antagonists - therapeutic use; Cohort Studies; Female; Humans; Medication Adherence; Middle Aged; Muscarinic Antagonists - therapeutic use; overactive blabber; Prospective Studies; questionnaire; Reproducibility of Results; Surveys and Questionnaires; Urinary Bladder, Overactive - drug therapy
• ISSN: 0733-2467; 1520-6777
• DOI: 10.1002/nau.22605

Aim To validate a self‐administered instrument, the Medication Adherence Self‐Report Inventory (MASRI) for measuring adherence to anti‐cholinergic medication for overactive bladder (OAB). Methods Prospective study in 131 women with OAB treated with fesoterodine. Adherence was measured at 8 and 12 weeks using an interviewer administered brief medication questionnaire (BMQ) that assesses barriers to adherence (criterion standard), the MASRI, and pill count. Construct, concurrent and discriminant validity of the MASRI was assessed. We hypothesized that women who were non‐adherent as measured by the MASRI would be more likely to have a belief barrier than women who were adherent to medication. Results Women diagnosed as non‐adherent by the MASRI were more likely to report a belief barrier to taking medication as compared to adherent women at 8 weeks (80% vs. 38%, P