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Prevalence and factors associated with tuberculosis treatment outcome among hazardous or harmful alcohol users in public primary health care in South Africa
Background: Tuberculosis (TB) remains a chronic infectious disease with high morbidity and mortality. Objective: The aim of this study was to assess the prevalence and associated factors of tuberculosis treatment failure, death and default among hazardous or harmful alcohol users. Method: We conduct...
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Published in: | African health sciences 2014-03, Vol.14 (1), p.157-166 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | Background: Tuberculosis (TB) remains a chronic infectious disease with
high morbidity and mortality. Objective: The aim of this study was to
assess the prevalence and associated factors of tuberculosis treatment
failure, death and default among hazardous or harmful alcohol users.
Method: We conducted a prospective study with TB patients in 40 public
health clinics in three districts in South Africa. All consecutively
new tuberculosis and retreatment patients presenting at the 40 primary
health care facilities with hazardous or harmful alcohol use were
included in this study. Logistic regression was used to assess
determinants of TB treatment failure, death and default. Results: The
findings of our study showed that 70% of TB patients were either cured
or had completed their TB treatment by the end of 6 months. In
multivariate analysis participants living in a shack or traditional
housing (Odds Ratio=OR: 0.63, Confidence Interval=CI: 0.45-0.89), being
a TB retreatment patient (OR: 1.61, CI: 1.15-2.26) and residing in the
eThekwini district (OR: 1.82, CI: 1.27-2.58) were significant
predictors of treatment failure, death and default. Conclusion: A high
rate of treatment failure, death and default were found in the TB
patients. Several factors were identified that can guide interventions
for the prevention of treatment failure, death and default. |
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ISSN: | 1680-6905 1729-0503 |
DOI: | 10.4314/ahs.v14i1.24 |