Genetic and Epigenetic Effects of Environmental Mutagens and Carcinogens

MicroRNAs are posttranscriptional regulators of gene expression involved in carcinogenesis, metastasis, and invasion. [...]microRNAs are potentially useful as diagnostic and prognostic biomarkers as well as anticancer therapeutic targets. [...]the alteration of microRNA expression is a general mecha...

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Bibliographic Details
Published in:BioMed research international 2015-01, Vol.2015, p.608054-3
Main Authors: Pulliero, Alessandra, Cao, Jia, Vasques, Luciana dos Reis, Pacchierotti, Francesca
Format: Article
Language:English
Subjects:
Animals
Biomedical research
Bisphenol A
Cancer
Carcinogenesis
Carcinogens, Environmental - adverse effects
Deoxyribonucleic acid
DNA
DNA methylation
Environmental health
Epigenesis, Genetic - drug effects
Epigenetic inheritance
Epigenetics
Fluorides
Gene expression
Genetic aspects
Genomes
Health aspects
Humans
Influence
Lifestyles
MicroRNAs
Mutagens
Mutagens - adverse effects
Observations
Studies
Toxicology
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Summary:MicroRNAs are posttranscriptional regulators of gene expression involved in carcinogenesis, metastasis, and invasion. [...]microRNAs are potentially useful as diagnostic and prognostic biomarkers as well as anticancer therapeutic targets. [...]the alteration of microRNA expression is a general mechanism playing an important pathogenic role in linking exposure to environmental toxic agents with their pathological consequences.
ISSN:2314-6133
2314-6141
DOI:10.1155/2015/608054