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Late initiation of combination antiretroviral therapy in Canada: a call for a national public health strategy to improve engagement in HIV care

Introduction Combination antiretroviral therapy (ART) significantly decreases morbidity, mortality and HIV transmission. We aimed to characterize the timing of ART initiation based on CD4 cell count from 2000 to 2012 and identify factors associated with late initiation of treatment. Methods Particip...

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Bibliographic Details
Published in:Journal of the International AIDS Society 2015-01, Vol.18 (1), p.20024-n/a
Main Authors: Cescon, Angela, Patterson, Sophie, Davey, Colin, Ding, Erin, Raboud, Janet M, Chan, Keith, Loutfy, Mona R, Cooper, Curtis, Burchell, Ann N, Palmer, Alexis K, Tsoukas, Christos, Machouf, Nima, Klein, Marina B, Rourke, Sean B, Rachlis, Anita, Hogg, Robert S, Montaner, Julio SG
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Language:English
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Summary:Introduction Combination antiretroviral therapy (ART) significantly decreases morbidity, mortality and HIV transmission. We aimed to characterize the timing of ART initiation based on CD4 cell count from 2000 to 2012 and identify factors associated with late initiation of treatment. Methods Participants from the Canadian Observational Cohort (CANOC), a multi‐site cohort of HIV‐positive adults initiating ART naively after 1 January 2000, in three Canadian provinces (British Columbia, Ontario and Québec) were included. Late initiation was defined as a CD4 count
ISSN:1758-2652
1758-2652
DOI:10.7448/IAS.18.1.20024