A randomized trial of diagnostic ultrasound to improve outcomes in focal neuropathies

ABSTRACT Introduction: Neuromuscular ultrasound is valid, reliable, and accurate, but it is not known whether combining it with electrodiagnostic studies leads to better outcomes in individuals with focal neuropathies. Methods: One hundred twenty individuals with focal neuropathy, based on history,...

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Published in:Muscle & nerve 2015-11, Vol.52 (5), p.746-753
Main Authors: Cartwright, Michael S., Griffin, Leah P., Dowlen, Hugh, Bargoil, Jessica M., Caress, James B., Li, Zhongyu J., Defranzo Jr, Anthony J., Wiesler, Ethan R., Tuohy, Christopher J., Balakrishnan, Nikhil, Molnar, Joseph A., Baute, Vanessa, Koman, L. Andrew, Poehling, Gary G., Walker, Francis O.
Format: Article
Language:English
Subjects:
Adult
Aged
carpal tunnel syndrome
Carpal Tunnel Syndrome - diagnostic imaging
Carpal Tunnel Syndrome - therapy
Electrodiagnosis - methods
Female
Humans
Male
Middle Aged
nerve
Neuromuscular Junction - diagnostic imaging
outcomes ultrasound
Treatment Outcome
Ulnar Neuropathies - diagnostic imaging
Ulnar Neuropathies - therapy
ulnar neuropathy at the elbow
Ultrasonic imaging
Ultrasonography
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Summary:ABSTRACT Introduction: Neuromuscular ultrasound is valid, reliable, and accurate, but it is not known whether combining it with electrodiagnostic studies leads to better outcomes in individuals with focal neuropathies. Methods: One hundred twenty individuals with focal neuropathy, based on history, examination, and electrodiagnosis, were enrolled in this study. All patients underwent neuromuscular ultrasound and were randomized to either have their ultrasound results sent to the referring physician or not have them sent. Outcomes were assessed at 6 months by evaluators blinded to group assignment. Results: The Overall Disability Sum Score and 7 of 8 domains of the Medical Outcomes Study 36‐item Short‐Form Health Survey (SF‐36) showed more improvement in the “report sent” group, although only the general health perception domain was significant (P = 0.005). Conclusions: Most 6‐month outcomes did not reach statistical significance between the 2 groups. However, the “report sent” group had trends toward better outcomes, with significance being reached in the general health perception domain of the SF‐36. Muscle Nerve 52: 746–753, 2015
ISSN:0148-639X
1097-4598
DOI:10.1002/mus.24884