Natural history of post-stroke apathy during acute rehabilitation

To better understand the natural history of post-stroke apathy, the authors tested 96 patients undergoing acute rehabilitation for stroke using the Apathy Inventory (AI). 28% of patients had apathy, and their AI scores improved on average 1 point by week 2 and 2 points by week 3 with the majority ap...

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Bibliographic Details
Published in:The journal of neuropsychiatry and clinical neurosciences 2015-01, Vol.27 (4), p.333-338
Main Authors: Kennedy, Juliana M., Granato, Dora A., Goldfine, Andrew M.
Format: Article
Language:English
Online Access:Get full text
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Summary:To better understand the natural history of post-stroke apathy, the authors tested 96 patients undergoing acute rehabilitation for stroke using the Apathy Inventory (AI). 28% of patients had apathy, and their AI scores improved on average 1 point by week 2 and 2 points by week 3 with the majority apathetic at discharge. Apathy severity correlated with aphasia, weakness, and impaired cognition, but not with depression. The findings suggest that acute rehabilitation is an optimal setting for clinical trials for post-stroke apathy because apathy is associated with poor outcomes and shows only a small degree of spontaneous improvement.
ISSN:0895-0172
1545-7222
DOI:10.1176/appi.neuropsych.15010001