Surface marker and other characteristics of Gaucher's cells

A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significanc...

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Bibliographic Details
Published in:Journal of clinical pathology 1977-10, Vol.30 (10), p.981-988
Main Authors: Burns, G F, Cawley, J C, Flemans, R J, Higgy, K E, Worman, C P, Barker, C R, Roberts, B E, Hayhoe, F G
Format: Article
Language:English
Subjects:
Cell Extracts - immunology
Child
Female
Gaucher Disease - immunology
Gaucher Disease - pathology
Humans
Leukocyte Count
Receptors, Antigen, B-Cell - analysis
Rosette Formation
Spleen - immunology
Spleen - ultrastructure
T-Lymphocytes - immunology
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Summary:A full surface marker study of the splenic storage cells in a case of Gaucher's disease largely substantiates the monocyte/histiocyte nature of Gaucher's cells. In addition, an apparent T-lymphocyte deficiency is demonstrated in the spleen and peripheral blood, and the possible significance of this finding is discussed.
ISSN:0021-9746
1472-4146
DOI:10.1136/jcp.30.10.981