Defibrillation time intervals and outcomes of cardiac arrest in hospital: retrospective cohort study from Get With The Guidelines-Resuscitation registry

Objective To describe temporal trends in the time interval between first and second attempts at defibrillation and the association between this time interval and outcomes in patients with persistent ventricular tachycardia or ventricular fibrillation (VT/VF) arrest in hospital.Design Retrospective c...

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Bibliographic Details
Published in:BMJ (Online) 2016-04, Vol.353, p.i1653-i1653
Main Authors: Bradley, Steven M, Liu, Wenhui, Chan, Paul S, Nallamothu, Brahmajee K, Grunwald, Gary K, Self, Alyssa, Sasson, Comilla, Varosy, Paul D, Anderson, Monique L, Schneider, Preston M, Ho, P Michael
Format: Article
Language:English
Subjects:
Aged
Cardiac arrest
Cardiac arrhythmia
Clinical outcomes
Data collection
Electric Countershock - statistics & numerical data
Female
Heart Arrest - therapy
Hospitals
Humans
Male
Medical records
Middle Aged
Models, Statistical
Outcome Assessment (Health Care)
Patients
Quality improvement
Retrospective Studies
Statistics, Nonparametric
Survival Analysis
Tachycardia, Ventricular - therapy
Time Factors
United States
Ventricular Fibrillation - therapy
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Summary:Objective To describe temporal trends in the time interval between first and second attempts at defibrillation and the association between this time interval and outcomes in patients with persistent ventricular tachycardia or ventricular fibrillation (VT/VF) arrest in hospital.Design Retrospective cohort studySetting 172 hospitals in the United States participating in the Get With The Guidelines-Resuscitation registry, 2004-12.Participants Adults who received a second defibrillation attempt for persistent VT/VF arrest within three minutes of a first attempt.Interventions Second defibrillation attempts categorized as early (time interval of up to and including one minute between first and second defibrillation attempts) or deferred (time interval of more than one minute between first and second defibrillation attempts).Main outcome measure Survival to hospital discharge.Results Among 2733 patients with persistent VT/VF after the first defibrillation attempt, 1121 (41%) received a deferred second attempt. Deferred second defibrillation for persistent VT/VF increased from 26% in 2004 to 57% in 2012 (P
ISSN:1756-1833
0959-8138
1756-1833
DOI:10.1136/bmj.i1653