Adaptive servoventilation versus oxygen therapy for sleep disordered breathing in patients with heart failure: a randomised trial

BackgroundBoth adaptive servoventilation (ASV) and nocturnal oxygen therapy improve sleep disordered breathing (SDB), but their effects on cardiac parameters have not been compared systematically.Methods and results43 patients with chronic heart failure (CHF; left ventricular ejection fraction (LVEF...

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Published in:Open heart 2016-03, Vol.3 (1), p.e000366-e000366
Main Authors: Murase, Kimihiko, Ono, Koh, Yoneda, Tomoya, Iguchi, Moritake, Yokomatsu, Takafumi, Mizoguchi, Tetsu, Izumi, Toshiaki, Akao, Masaharu, Miki, Shinji, Nohara, Ryuji, Ueshima, Kenji, Mishima, Michiaki, Kimura, Takeshi, White, David P, Chin, Kazuo
Format: Article
Language:English
Subjects:
Beta blockers
Heart failure
Heart Failure and Cardiomyopathies
Mortality
Oxygen
Oxygen therapy
Physicians
Respiratory therapy
Sleep
Studies
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Summary:BackgroundBoth adaptive servoventilation (ASV) and nocturnal oxygen therapy improve sleep disordered breathing (SDB), but their effects on cardiac parameters have not been compared systematically.Methods and results43 patients with chronic heart failure (CHF; left ventricular ejection fraction (LVEF) ≤50%) with SDB were randomly assigned to undergo ASV (n=19, apnoea hypopnoea index (AHI)=34.2±12.1/h) or oxygen therapy (n=24, 36.9±9.9/h) for 3 months. More than 70% of SDB events in both groups were central apnoeas or hypopnoeas. Although nightly adherence was less for the ASV group than for the oxygen group (4.4±2.0 vs 6.2±1.8 h/day, p
ISSN:2053-3624
2398-595X
2053-3624
DOI:10.1136/openhrt-2015-000366