The Relieving Effects of BrainPower Advanced, a Dietary Supplement, in Older Adults with Subjective Memory Complaints: A Randomized, Double-Blind, Placebo-Controlled Trial

Subjective memory complaints (SMCs) are common in older adults that can often predict further cognitive impairment. No proven effective agents are available for SMCs. The effect of BrainPower Advanced, a dietary supplement consisting of herbal extracts, nutrients, and vitamins, was evaluated in 98 v...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2016-01, Vol.2016 (2016), p.1-16
Main Authors: Ye, Yeats, Rao, Jianyu, Xing, Guoqiang, Shariff, Mina, Gu, Pingping, Feng, Yi, Shen, Tian, Dai, Lihua, Chen, Su, Shi, Rong, Zhu, Jingfen, Nguyen, Tuong
Format: Article
Language:English
Subjects:
Aging
Binding sites
Brain research
Clinical trials
Cognition & reasoning
Cognitive ability
Community health care
Complaints
Dietary supplements
Hospitals
Ingredients
Medical imaging
Medicine
Memory
Older people
Public health
Rodents
Studies
Young adults
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Summary:Subjective memory complaints (SMCs) are common in older adults that can often predict further cognitive impairment. No proven effective agents are available for SMCs. The effect of BrainPower Advanced, a dietary supplement consisting of herbal extracts, nutrients, and vitamins, was evaluated in 98 volunteers with SMCs, averaging 67 years of age (47–88), in a randomized, double-blind, placebo-controlled trial. Subjective hypomnesis/memory loss (SML) and attention/concentration deficits (SAD) were evaluated before and after 12-week supplementation of BrainPower Advanced capsules (n=47) or placebo (n=51), using a 5-point memory questionnaire (1 = no/slight, 5 = severe). Objective memory function was evaluated using 3 subtests of visual/audio memory, abstraction, and memory recall that gave a combined total score. The BrainPower Advanced group had more cases of severe SML (severity ⩾ 3) (44/47) and severe SAD (43/47) than the placebo group (39/51 and 37/51, < 0.05, < 0.05, resp.) before the treatment. BrainPower Advanced intervention, however, improved a greater proportion of the severe SML (29.5%)(13/44) (P
ISSN:1741-427X
1741-4288
DOI:10.1155/2016/7898093