When Computer Simulation Excels Experiment

For many biophysical problems we have, in general, two approaches. A problem can be studied experimentally, or the corresponding system can be simulated. So far, for the great majority of problems, simulation cannot compete with experiment. Still, simulation seems very attractive because if we solve...

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Bibliographic Details
Published in:Biophysical journal 2016-05, Vol.110 (10), p.2136-2137
Main Author: Vologodskii, Alexander
Format: Article
Language:English
Subjects:
Computer Simulation
Deoxyribonucleic acid
Design of experiments
DNA
Effectiveness
New and Notable
Simulation
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Summary:For many biophysical problems we have, in general, two approaches. A problem can be studied experimentally, or the corresponding system can be simulated. So far, for the great majority of problems, simulation cannot compete with experiment. Still, simulation seems very attractive because if we solve a problem this way, we can obtain much more interesting additional information about the system. This can be seen in the field of large-scale conformational properties of DNA where simulation and experiment compete successfully and, of course, complement each other.
ISSN:0006-3495
1542-0086
DOI:10.1016/j.bpj.2016.04.016