Glycosylation Quality Control by the Golgi Structure

Glycosylation is a ubiquitous modification that occurs on proteins and lipids in all living cells. Consistent with their high complexity, glycans play crucial biological roles in protein quality control and recognition events. Asparagine-linked protein N-glycosylation, the most complex glycosylation...

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Bibliographic Details
Published in:Journal of molecular biology 2016-08, Vol.428 (16), p.3183-3193
Main Authors: Zhang, Xiaoyan, Wang, Yanzhuang
Format: Article
Language:English
Subjects:
Animals
Biological Transport - physiology
CDG
COG complex
endoplasmic reticulum
Endoplasmic Reticulum - metabolism
Endoplasmic Reticulum - physiology
glucose transporters
glycosidases
Glycosylation
glycosyltransferases
Golgi apparatus
Golgi Apparatus - metabolism
Golgi Apparatus - physiology
Golgi stacks
GRASPs
Humans
lipids
mammals
Membrane Proteins - metabolism
polysaccharides
protein glycosylation
protein transport
Protein Transport - physiology
quality control
sugars
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