Prehypertension Is Associated With Abnormalities of Cardiac Structure and Function in the Atherosclerosis Risk in Communities Study

BACKGROUND Prehypertension (blood pressure (BP) of 120–139mm Hg systolic and/or 80–89mm Hg diastolic) is highly prevalent and is associated with increased cardiovascular risk. Our goal was to investigate the extent to which prehypertension is associated with end-organ alterations in cardiac structur...

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Bibliographic Details
Published in:American journal of hypertension 2016-05, Vol.29 (5), p.568-574
Main Authors: Santos, Angela B.S., Gupta, Deepak K., Bello, Natalie A., Gori, Mauro, Claggett, Brian, Fuchs, Flavio D., Shah, Amil M., Coresh, Josef, Sharrett, A. Richey, Cheng, Susan, Solomon, Scott D.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Blood Pressure
Cross-Sectional Studies
Diastole
Echocardiography, Doppler
Female
Heart
Humans
Hypertrophy, Left Ventricular - diagnostic imaging
Hypertrophy, Left Ventricular - epidemiology
Hypertrophy, Left Ventricular - physiopathology
Male
Middle Aged
Original
Prehypertension - diagnosis
Prehypertension - epidemiology
Prehypertension - physiopathology
Prevalence
Prospective Studies
Risk Factors
United States - epidemiology
Ventricular Dysfunction, Left - diagnostic imaging
Ventricular Dysfunction, Left - epidemiology
Ventricular Dysfunction, Left - physiopathology
Ventricular Function, Left
Ventricular Remodeling
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Summary:BACKGROUND Prehypertension (blood pressure (BP) of 120–139mm Hg systolic and/or 80–89mm Hg diastolic) is highly prevalent and is associated with increased cardiovascular risk. Our goal was to investigate the extent to which prehypertension is associated with end-organ alterations in cardiac structure and function in a large biracial cohort of older men and women. METHODS We studied 4,871 participants of the Atherosclerosis Risk in Communities (ARIC) study who attended visit 5 (2011–2013) and underwent two-dimensional echocardiography while free of prevalent coronary heart disease or heart failure. We categorized participants into 3 groups: optimal BP (BP
ISSN:0895-7061
1941-7225
DOI:10.1093/ajh/hpv156