The Changing Pattern of Diagnosing Primary Hyperparathyroidism in Young Patients

Abstract Background Primary hyperparathyroidism (PHPT) is increasing in adults, but rarely reported in young patients where routine blood work is obtained more judiciously. We aim to determine how PHPT is currently being diagnosed in young patients and examine surgical outcomes. Method We retrospect...

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Bibliographic Details
Published in:The American journal of surgery 2017-01, Vol.213 (1), p.146-150
Main Authors: Lou, Irene, MD, Schneider, David F., MD, MS, Sippel, Rebecca S., MD, Chen, Herbert, MD, Elfenbein, Dawn M., MD, MPH
Format: Article
Language:English
Subjects:
Abdomen
Adolescent
Adolescent hyperparathyroidism
Age
Age Factors
Child
Family medical history
Female
Health risk assessment
Humans
Hyperparathyroidism, Primary - complications
Hyperparathyroidism, Primary - diagnosis
Hyperparathyroidism, Primary - surgery
Incidental Findings
Kidney stones
Male
Pain
Parathyroidectomy
Patients
Pediatric hyperparathyroidism
Population
Primary hyperparathyroidism
Retrospective Studies
Surgery
Tumors
Young Adult
Young adults
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Summary:Abstract Background Primary hyperparathyroidism (PHPT) is increasing in adults, but rarely reported in young patients where routine blood work is obtained more judiciously. We aim to determine how PHPT is currently being diagnosed in young patients and examine surgical outcomes. Method We retrospectively analyzed PHPT patients ≤ 24 years who underwent parathyroidectomy from 2001-2014. Patients were divided into two time-periods: 2001-2007 (A) and 2008-2014 (B). Incidentally diagnosed patients lacked objective symptoms of PHPT and had no family history. Results 40 young patients met inclusion criteria: 16 in group A and 24 in group B. Those in group A compared to group B had similar mean age, preoperative calcium and parathyroid hormone (p>0.05). Incidental diagnosis was more common in the contemporary group (42% vs 25%, p=0.001). Conclusion Current diagnosis of PHPT in young patients is increasingly incidental. This trend may be attributed to the more liberal use of labs in younger patients.
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2016.03.019