The impact of esophagogastric varices on the prognosis of patients with hepatocellular carcinoma

Whether or not esophagogastric varices (EGV) could determine the outcomes of patients with hepatocellular carcinoma (HCC) is still unclear. A total of 990 treatment-naive HCC patients who received an esophagogastroduodenoscopy at the time of HCC diagnosis were retrospectively enrolled. The factors i...

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Published in:Scientific reports 2017-02, Vol.7 (1), p.42577-42577, Article 42577
Main Authors: Hsieh, Wei-Yao, Chen, Ping-Hsien, Lin, I-Yen, Su, Chien-Wei, Chao, Yee, Huo, Teh-Ia, Huang, Yi-Hsiang, Hou, Ming-Chih, Lin, Han-Chieh, Wu, Jaw-Ching
Format: Article
Language:English
Subjects:
692/4020/4021/1607/1604
692/4020/4021/1607/1610/4029
Hepatocellular carcinoma
Humanities and Social Sciences
Liver cancer
Medical prognosis
multidisciplinary
Multivariate analysis
Prognosis
Science
Survival
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Summary:Whether or not esophagogastric varices (EGV) could determine the outcomes of patients with hepatocellular carcinoma (HCC) is still unclear. A total of 990 treatment-naive HCC patients who received an esophagogastroduodenoscopy at the time of HCC diagnosis were retrospectively enrolled. The factors in terms of prognosis were analyzed by Cox proportional hazards model and propensity score matching analysis. Among the enrolled patients, 480 (48.5%) patients had EGV. Patients with EGV had a significantly lower cumulative 5-year survival rate than those without EGV (24.9% versus 46.4%, p  
ISSN:2045-2322
2045-2322
DOI:10.1038/srep42577