Detecting Swelling States of Red Blood Cells by “Cell–Fluid Coupling Spectroscopy”

Red blood cells are “shaken” with a holographic optical tweezer array. The flow generated around cells due to the periodic optical forcing is measured with an optically trapped “detector” particle located in the cell vicinity. A signal‐processing model that describes the cell's physical propert...

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Bibliographic Details
Published in:Advanced science 2017-02, Vol.4 (2), p.1600238-n/a
Main Authors: Zensen, Carla, Fernandez, Isis E., Eickelberg, Oliver, Feldmann, Jochen, Lohmüller, Theobald
Format: Article
Language:English
Subjects:
Blood
cell–fluid interaction
Communication
Communications
cytometry
Experiments
Lasers
Mechanical properties
Medical research
microfluidics
Microscopy
optical tweezers
Sensors
Signal processing
Spectrum analysis
Time series
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Description
Summary:Red blood cells are “shaken” with a holographic optical tweezer array. The flow generated around cells due to the periodic optical forcing is measured with an optically trapped “detector” particle located in the cell vicinity. A signal‐processing model that describes the cell's physical properties as an analog filter illustrates how cells can be distinguished from each other.
ISSN:2198-3844
2198-3844
DOI:10.1002/advs.201600238