The effect of acupuncture on chemotherapy-associated gastrointestinal symptoms in gastric cancer

• Published in: Current oncology (Toronto) 2017-02, Vol.24 (1), p.e1-5
• Main Authors: Zhou, J, Fang, L, Wu, W Y, He, F, Zhang, X L, Zhou, X, Xiong, Z J
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 1198-0052; 1718-7729; 1718-7729
• DOI: 10.3747/co.24.3296

Gastrointestinal (gi) symptoms are the most notable side effects of chemotherapeutic drugs; such symptoms are currently treated with drugs. In the present study, we investigated the effect of acupuncture on gi symptoms induced by chemotherapy in patients with advanced gastric cancer. A cohort of 56 patients was randomly divided into an experimental group and a control group. All patients received combination chemotherapy with oxaliplatin-paclitaxel. Patients in the experimental group received 30 minutes of acupuncture therapy daily for 2 weeks. The frequency and duration of nausea, vomiting, abdominal pain, and diarrhea, the average days and costs of hospitalization, and quality-of-life scores were compared between the groups. Nausea was sustained for 32 ± 5 minutes and 11 ± 3 minutes daily in the control and experimental groups respectively ( < 0.05). On average, vomiting occurred 2 ± 1 times daily in the experimental group and 4 ± 1 times daily in the control group ( < 0.05). Abdominal pain persisted for 7 ± 2 minutes and 16 ± 5 minutes daily in the experimental and control groups respectively ( < 0.05). On average, diarrhea occurred 1 ± 1 times daily in the experimental group and 3 ± 1 times daily in the control group ( < 0.05). The average quality-of-life score was higher in the experimental group than in the control group ( < 0.05). No adverse events were observed for the patients receiving acupuncture. Acupuncture, a safe technique, could significantly reduce gi symptoms induced by chemotherapy and enhance quality of life in patients with advanced gastric cancer.