Concurrent with T-zone lymphoma and high-grade gastrointestinal cytotoxic T-cell lymphoma in a dog

A 9-year-old, spayed female Golden Retriever dog was referred to us for lymphocytosis and lymphadenopathy, secondary to suspected chronic lymphocytic leukemia (CLL). The dog had a clinical history of anorexia, vomiting and melena lasting two days. The popliteal lymph node contained small-to-intermed...

Full description

Saved in:
Bibliographic Details
Published in:Journal of Veterinary Medical Science 2017, Vol.79(4), pp.736-739
Main Authors: SUWA, Akihisa, SHIMODA, Tetsuya
Format: Article
Language:English
Subjects:
Animals
canine
Clinical Pathology
Dog Diseases - immunology
Dogs
Female
gastrointestinal lymphoma
Gastrointestinal Neoplasms - immunology
Gastrointestinal Neoplasms - veterinary
large granular lymphocytic lymphoma
Lymphoma, T-Cell - immunology
Lymphoma, T-Cell - veterinary
Neoplasms, Multiple Primary - immunology
Neoplasms, Multiple Primary - veterinary
PARR
T-Lymphocytes, Cytotoxic - immunology
T-zone lymphoma
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 9-year-old, spayed female Golden Retriever dog was referred to us for lymphocytosis and lymphadenopathy, secondary to suspected chronic lymphocytic leukemia (CLL). The dog had a clinical history of anorexia, vomiting and melena lasting two days. The popliteal lymph node contained small-to-intermediate lymphocytes, which led us to suspect low-grade lymphoma. Thickened lesions in the stomach and small intestine were detected by ultrasonography. Histopathology of the popliteal lymph node and small intestine revealed a simultaneous presence of T-zone lymphoma (TZL) and high-grade gastrointestinal (GI) cytotoxic T-cell lymphoma. Large granular lymphocytes (LGLs) were seen on cytological examination. Polymerase chain reaction (PCR) revealed that both lymphomas originated in the T-cells. The dog died 15 days after diagnosis, despite chemotherapy.
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.16-0542